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Gavathiotis E, Suzuki M, Davis ML, Pitter K, Bird GH, Katz SG, Tu H-C, Kim H, Cheng EH-Y, Tjandra N and Walensky LD. BAX activation is initiated at a novel interaction site. Nature 2008, 455:1076-81. |
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Pitter K, Bernal F, LaBelle J and Walensky LD. Chapter 23: Dissection of the BCL-2 family signaling network with Stabilized Alpha-Helices of BCL-2 domains. Methods in Enzymology 2008, 446:387-408. |
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Bird GH, Bernal F, Pitter K and Walensky LD. Chapter 22: Synthesis and biophysical characterization of Stabilized Alpha-Helices of BCL-2 domains. Methods in Enzymology 2008, 446:369-86. |
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Danial NN, Walensky LD, Chang C-Y, Choi CS, Fisher JK, et al. Dual role of proapoptotic BAD in insulin secretion and beta cell survival. Nature Med. 2008, 14:144-53. |
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Verdine GL and Walensky LD.The challenge of drugging undruggable targets in cancer: Lessons learned from targeting BCL-2 family members. Clin. Cancer Res. 2007, 13:7264-7270. |
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Bernal F, Tyler AF, Korsmeyer SJ, Walensky LD, Verdine GL. Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide. J Am Chem Soc. 2007,129:2456-7. |
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Walensky LD, Pitter K, Morash J, Oh KJ, Barbuto S, Fisher J, Smith E, Verdine GL, Korsmeyer SJ. A stapled BID BH3 helix directly binds and activates BAX. Mol Cell. 2006, 24:199-210.
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Oh KJ, Barbuto S, Pitter K, Morash J, Walensky LD, Korsmeyer SJ. A membrane-targeted BID BCL-2 homology 3 peptide is sufficient for high potency activation of BAX in vitro. J Biol Chem. 2006, 281:36999-7008. |
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Walensky LD. BCL-2 in the crosshairs: tipping the balance of life and death. Cell Death Differ. 2006, 13:1339-50. |
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Walensky LD, Kung AL, Escher I, Malia TJ, Barbuto S, Wright RD, Wagner G, Verdine GL, Korsmeyer SJ. Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix. Science. 2004, 305:1466-70. |
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