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The Walensky Lab: Stapled BCL-2 Peptides
The Walensky laboratory focuses on the chemical biology of deregulated apoptotic and transcriptional pathways in cancer. Our goal is to develop an arsenal of new compounds-a “chemical toolbox”-to investigate and block protein interactions that cause cancer. To achieve these objectives, we take a multidisciplinary approach that employs synthetic chemistry techniques, structural biology analyses, and biochemical, cellular, and mouse modeling experiments to systematically dissect the pathologic signaling pathways of interest.
Recent News
Seeking Your Talent!
Monday, 19 December 2011
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We are currently seeking candidates to fill the following positions in our laboratory:
1. Postdoctoral Fellows: The Walensky laboratory is seeking highly accomplished PhD graduates applying for postdoctoral fellowship training in cancer chemical biology.  We are particularly interested in candidates with deep expertise in structural biology, proteomics, molecular and cellular biology, or mouse modeling.
2. Science Writer: This position is geared to experienced basic science writers or editors who are interested in part-time or full-time work for a dynamic multidisciplinary laboratory.  Work tasks would include the design, preparation, and editing of manuscripts, grants, and other scientific documents. PhD level experience in science or english, and deep experience in science writing as a basic scientist or journal editor is required.
3. Laboratory Operations Manager: The Walensky laboratory is seeking a PhD-level scientist or MBA-trained manager to work hand-in-hand with Dr. Walensky to manage a diversity of laboratory research programs and initiatives.  Experience with personnel management, database/software development, scientific project leadership, computational biology, and business administration are key criteria for this position.
Applicants should submit a CV, career goals statement, and three letters of reference by email to Sharon Gittens ( This e-mail address is being protected from spam bots, you need JavaScript enabled to view it )   
 
How can we help?
Thursday, 01 December 2011
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Our laboratory specializes in the design, synthesis, and application of stapled alpha-helical peptides for biomedical research. We are pleased to participate in academic collaborations by designing and generating stapled peptides for your research needs.  Our goal is to remain fully engaged with our collaborators to provide ongoing input on experimental design, data analysis, and project development. Charges to the investigator are for synthesis costs only and approximate core facility fees for standard peptide synthesis. Submit your project proposals by email to Greg Bird ( This e-mail address is being protected from spam bots, you need JavaScript enabled to view it )  
 
San Francisco Here She Comes
Sunday, 16 October 2011
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Congratulations to Lauren Barclay for her participation in the Nike Women's Marathon, A Race to Benefit the Leukemia and Lymphoma Society. We are so proud of your accomplishment!
 
Sam Katz Awarded a Lymphoma Research Foundation Grant
Monday, 01 August 2011
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Congratulations to Sam Katz for being awarded a Lymphoma Research Foundation grant to support his research on the pathogenesis and treatment of mantle cell lymphoma.
 
Welcome Silvia Escudero
Friday, 01 July 2011
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The Walensky laboratory welcomes its newest graduate student member from the Biological and Biomedical Sciences program at Harvard Medical School.