Research Interest
We are trying to understand how cytoskeleton undergoes a dramatic rearrangement during the cell cycle. My research focuses on a molecular link between cell cycle regulators and cytoskeletal proteins. Among various candidates, Kinases and GTPases are my favorite targets.
Education
| 2003–2009 | Postdoctoral fellowship in the laboratory of David Pellman, Dana Farber Cancer Institute |
| 2003 | PhD, University of Tokyo. Tokyo, Japan |
| 1998 | BS, University of Tokyo. Tokyo, Japan |
Selected publications
- Yoshida S, Bartolini S, Pellman D. Mechanisms for concentrating Rho1 during cytokinesis.Genes Dev. (2009)
- Atkins BD, Yoshida S, Pellman D.Symmetry Breaking: Scaffold Plays Matchmaker for Polarity Signaling Proteins. Current Biology (2008)
- Yoshida S, Pellman D.Plugging the GAP between cell polarity and cell cycle.EMBO Reports (2008) Jan;9(1):39-41
- Buttery SM, Yoshida S, Pellman D.Yeast formins Bni1 and Bnr1 utilize different modes of cortical interactionduring the assembly of actin cables.Mol Biol Cell (2007) May;18(5):1826-38
- Yoshida S, Kono K, Lowery DM, Bartolini S, Yaffe MB, Ohya Y & Pellman D.Polo-Like Kinase Cdc5 Controls the Local Activation of Rho1 to Promote Cytokinesis.Science (2006), 312 (5782) 108-111
- Yoshida S, Guillet M, & Pellman D. MEN signaling: daughter bound pole must escape her mother to be fully active. Dev Cell. (2005), 9(2)168–170
- Yoshida S, Ichihashi R, & Toh-e, A. Ras recruites mitotic exit regulator Lte1 to the bud cortex in budding yeast. Journal of Cell Biology (2003), 161(5):889–97
- Yoshida S, Asakawa K, & Toh-e, A. "Mitotic exit network controls the localization of Cdc14 to the spindle pole body in Saccharomyces cerevisiae" Current Biology (2002), 14: 944–50
- Yoshida S, & Toh-e, A. Budding yeast Cdc5 phosphorylates Net1 and regulates Cdc14 release from the nucleolus. Biochem. Biophys. Res. Comm. (2002), 294: 687–91
