Research Interest
Mijung Kwon is interested in finding out how mitosis works in normal and cancer cells, and how such insight can be used to develop selective anti-cancer drugs.
Being interested in deciphering how cancer cells prevent chaotic mitoses in the presence of extra centrosomes, her research is focused on identifying molecular machinery
to organize extra centrosomes using functional genomic approaches. Currently, detailed molecular mechanisms are being investigated.
Education
| 2009–present | Leukemia and Lymphoma Society Special Fellow, DFCI |
| 2006–2009 | Susan Komen Foundation Postdoctoral Fellowship, DFCI |
| 2004–present | Postdoctoral fellowship in the laboratory of David Pellman, Dana Farber Cancer Institute |
| 2003 | PhD in Cell and Developmental Biology, University of California Davis. Davis, CA |
| 1996 | MS in Cell Biology, Ewha Woman's University. Seoul, Korea |
| 1994 | BS in Biology, Ewha Woman's University. Seoul, Korea |
Selected publications
- Godinho SA*, Kwon M*, Pellman D. Centrosomes and cancer: how cancer cells divide with too many centrosomes.Cancer Metastasis Rev. (2009)
- Kwon M*,Godinho SA*, Chandhok NS, Ganem NJ, Azioune A, Thery M, Pellman D.Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes.Genes Dev. (2008) Aug 15;22(16):2189-203
- Kwon M, & Scholey JM. Spindle mechanics and dynamics during mitosis in Drosophila. Trends Cell Biol (2004), 14(4):194–205
- Kwon M, Morales-Mulia S, Brust-Mascher I, Rogers GC, Sharp DJ, & Scholey JM. The chromokinesin, KLP3A, dives mitotic spindle pole separation during prometaphase and anaphase and facilitates chromatid motility. Mol Biol Cell (2004), 15(1):219–33
- Brust-Mascher I, Civelekoglu-Scholey G, Kwon M, Mogilner A, Scholey JM.Model for anaphase B: role of three mitotic motors in a switch from poleward flux to spindle elongation.Proc Natl Acad Sci U S A (2004) Nov 9;101(45):15938-43.
- Kwon, M., Seo, S., Chun, H., Chung, J.M., Chung, I.K., and Hur, K.C. Dual effect of nerve growth factor on cell death of PC12 cells induced by serum deprivation. Mol Cells (2002) 13(2):167-74
- Sharp DJ, Brown HM, Kwon M, Rogers GC, Holland G, & Scholey JM. Functional coordination of three mitotic motors in Drosophila embryos. Mol Biol Cell (2000), 11(1):241–53
