Research Interest
In eukaryotes, cell morphogenesis is highly organized by various signaling pathways during the cell cycle. Focusing on the phase-specific regulation of the actin and microtubule cytoskeletons, we are trying to understand the signaling pathways essential for proper cell morphogenesis in budding yeast.
Education
| 2005–present | Postdoctoral fellowship in the laboratory of David Pellman, Dana Farber Cancer Institute |
| 2005 | PhD, University of Tokyo. Tokyo, Japan |
| 2000 | BA, University of Tokyo. Tokyo, Japan |
Selected publications
- Kono K, Nogami S, Abe M, Nishizawa M, Morishita S, Pellman D, Ohya Y.G1/S cyclin-dependent kinase regulates small GTPase Rho1p through phosphorylation of RhoGEF Tus1p in Saccharomyces cerevisiae.Mol Biol Cell (2008) Apr;19(4):1763-71
- Yoshida S, Kono K, Lowery DM, Bartolini S, Yaffe MB, Ohya Y & Pellman D.Polo-Like Kinase Cdc5 Controls the Local Activation of Rho1 to Promote Cytokinesis.Science (2006), 312 (5782) 108-111
- Kono K, Matsunaga R, Hirata A, Suzuki G, Abe M, Ohya Y. Involvement of actin and polarisome in morphological change during spore germination of Saccharomyces cerevisiae. Yeast (2005). 22:129–39
- Sekiya-Kawasaki M, Abe M, Saka A, Watanabe D, Kono K, Minemura-Asakawa M, Ishihara S, Watanabe T, Ohya Y. Dissection of upstream regulatory components of the Rho1p effector, 1,3-beta-glucan synthase, in Saccharomyces cerevisiae. Genetics (2002). 162:663–76
