Karen Crasta, PhD

karen_crasta@dfci.harvard.edu

Education

2008–present	Postdoctoral fellowship in the laboratory of David Pellman, Dana Farber Cancer Institute
2008	PhD, IMCB- National University of Singapore, Singapore
1999	BSc Hon (Microbiology), National University of Singapore, Singapore

Selected publications

• Crasta K, Lim HH, Giddings TH Jr, Winey M, Surana U.Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle.Nat Cell Biol (2008) Jun;10(6):665-75.
• Crasta K, Huang P, Morgan G, Winey M, Surana U.Cdk1 regulates centrosome separation by restraining proteolysis of microtubule-associated proteins.EMBO J (2006) Jun 7;25(11):2551-63.
• Krishnan V, Nirantar S, Crasta K, Cheng AY, Surana U.DNA replication checkpoint prevents precocious chromosome segregation by regulating spindle behavior.Mol Cell (2004) Dec 3;16(5):687-700.
• Crasta KC, Chua KL, Subramaniam S, Frey J, Loh H, Tan HM.Identification and characterization of CAMP cohemolysin as a potential virulence factor of Riemerella anatipestifer.J Bacteriol (2002) Apr;184(7):1932-9.