Postdoctoral fellowship in the laboratory of David Pellman, Dana Farber Cancer Institute
Selected publications
Sciarretta, K.L., Boire, A., Gordon, D.J. & Meredith, S.C. Spatial separation of beta-sheet domains of beta-amyloid: disruption of each beta-sheet by N-methyl amino acids. Biochemistry.(2006)
Sciarretta, K.L., Gordon D.J. & Meredith SC. Peptide-based inhibitors of amyloid assembly. Methods Enzymol. (2006)
Sciarretta, K. L., Gordon, D. J., Petkova, A.T., Tycko, R. & Meredith, S. C. Abeta40-lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid. Biochemistry.(2005)
Gordon, D.J., Balbach, J.J., Tycko R. & Meredith S.C. Increasing the Amphiphilicity of an Amyloidgenic Peptide Switches the ?-Strand Orientation in the Fibril from Antiparallel to Parallel. Biophys J.(2004)
Gordon, D.J. & Meredith S.C. Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions. Biochemistry (2003)
Balbach, J.J., Petkova A.T., Oyler N.A., Antzutkin O.N., Gordon D.J., Meredith S.C. & Tycko R. Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance. Biophys J. (2002)
Ryan W.L., Gordon D.J. & Levy D.H. Gas-phase photochemistry of the photoactive yellow protein chromophore trans-p-coumaric acid. J Am Chem Soc. (2002)
Gordon, D.J., Sciarretta, K. L. & Meredith, S. C. Inhibition of beta-amyloid(40) fibrillogenesis and disassembly of beta-amyloid(40) fibrils by short beta-amyloid congeners containing N-methyl amino acids at alternate residues. Biochemistry.(2001)
Gordon, D.J., Tappe, R. & Meredith, S. C. Inhibition of Beta-sheet Protein-Protein Interactions by Peptides Containing N-Methyl Amino Acids at Alternate Positions. Disruption of Beta-Amyloid Peptide Fibrillogenesis. J Pept Res. (2002)
Mustafi, D., Sosa-Peinado, A., Gupta, V., Gordon, D. J. & Makinen, M. W. Structure of spin-labeled methylmethanethiolsulfonate in solution and bound to TEM-1 beta-lactamase determined by electron nuclear double resonance spectroscopy. Biochemistry. (2002)
Kim, S. H., Wang, R., Gordon, D.J., Bass, J., Steiner, D. F., Thinakaran, G., Lynn, D. G., Meredith, S. C. & Sisodia, S. S. Familial British dementia: Expression and metabolism of BRI. In Molecular Basis of Dementia (2000)
Thiyagarajan, P., Burkoth, T. S., Urban, V., Seifert, S., Benzinger, T. L. S., Morgan, D. M., Gordon, D., Meredith, S. C. & Lynn, D.G. pH dependent self assembly of beta-amyloid(10-35) and beta- amyloid(10-35)PEG3000. Journal of Applied Crystallography. (2000)
Kim, S. H., Wang, R., Gordon, D. J., Bass, J., Steiner, D. F., Lynn, D. G., Thinakaran, G., Meredith, S. C. & Sisodia, S. S. Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia. Nature Neuroscience (1999)
Vymazal, J., Brooks, R. A., Bulte, J. W. M., Gordon, D. & Aisen, P. Iron uptake by ferritin: NMR relaxometry studies at low iron loads. Journal of Inorganic Biochemistry. (1998)
