Antibody Phage Display Technical Papers

  1. de Bruin R, Spelt K, Mol J, Koes R, Quattrocchio F. Selection of high-affinity phage antibodies from phage display libraries. Nat Biotechnol. 1999 Apr;17(4):397-9.
  2. Harrison JL, Williams SC, Winter G, Nissim A. Screening of phage antibody libraries. Methods Enzymol. 1996;267:83-109.
  3. O’Connell D, Becerril B, Roy-Burman A, Daws M, and Marks JD. Phage vesus Phagemid Libraries for Generation of Human Monoclonal Antibodies. J. Mol. Biol. 321:49-56, 2002.

Selection of Phage Antibodies to Cell Surface Determinants

  1. Marks JD, Ouwehand WH, Bye JM, Finnern R, Gorick BD, Voak D, Thorpe SJ, Hughes-Jones NC, Winter G. Human antibody fragments specific for human blood group antigens from a phage display library. Biotechnology (N Y). 1993 Oct;11(10):1145-9.
  2. Palmer DB, George AJ, Ritter MA. Selection of antibodies to cell surface determinants on mouse thymic epithelial cells using a phage display library. Immunology. 1997 Jul;91(3):473-8.
  3. Tur MK, Huhn M, Sasse S, Engert A, Barth S. Selection of scFv phages on intact cells under low pH conditions leads to a significant loss of insert-free phages. Biotechniques. 2001 Feb;30(2):404-8, 410, 412-3.

Large Phage Antibody Libraries

  1. Nissim A, Hoogenboom HR, Tomlinson IM, Flynn G, Midgley C, Lane D and Winter G. Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents. EMBO J. 1994 Feb 1;13(3):692-8.
  2. Griffiths AD, Williams SC, Hartley O, Tolinson IM, Waterhouse P, Crosby WL, Kontermann RE, Jones PT, Low NM, Allison TJ, Prospero TD, Hoogenboom HR, Nissim A, Cox JPL, Harrison JL, Zaccolo M, Gherardi E and Winter G. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J. 1994 Jul 15;13(14):3245-60.
  3. Sheets MD, Amersdorfer P, Finnern R, Sargent P, Lindqvist E, Schier R, Hemingsen G, Wong C, Gerhart JC, and Marks JD. Efficient construction of a large nonimmune phage antibody library: The production of high-affinity human single-chain antibodies to protein antigens. Proc Natl Acad Sci U S A. 1998 May 26;95(11):6157-62.
  4. de Kruif J, Boel E, Logtenberg T. Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions. J Mol Biol. 1995 Apr 21;248(1):97-105.
  5. Vaughan TJ, Williams AJ, Pritchard K, Osbourn JK, Pope AR, Earnshaw JC, McCafferty J, Hodits RA, Wilton J and Johnson KS. Human Antibodies with Sub-nonomolar Affinities Isolated form a Large Non-immunized Phage Display Library. Nat Biotechnol. 1996 Mar;14(3):309-14.
  6. deHaard HJ, van Neer N, Reurs A, Hufton SE, Roovers RC, Henderikn P, de Bruïne AP, Arends J-W and Hoogenboom HR. A large Non-immunized Human Fab Fragment Phage Library that Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies J Biol Chem. 1999 Jun 25;274(26):18218-30.

Antibody Engineering Reviews

  1. van Dijk MA and van de Winkel JGJ. Human antibodies as next generation therapeutics. Current Opin. Chem. Biol. 5:368-374, 2001.
  2. Hoogenboom HR, de Bruine AP, Hufton SE, Hoet RM, Arends JW, Roovers RC. Antibody phage display technology and its applications. Immunotechnology Jun;4(1):1-20, 1998.
  3. Dall'Acqua W, Carter P. Antibody Engineering. Curr Opin Struct Biol. Aug;8(4):443-50, 1998.
  4. Hudson PJ, Souriau C. Engineered antibodies. Nature Medicine 9, 129 – 134, 2003.

Intrabody Reviews

  1. Zhu Q, Marasco WA. Intracellular targeting of antibodies in mammalian cells. In New Comprehensive Biocehmistry : Gene Transfer and Expression in Mammalian Cells. Ed. Savvas C. Makrides, Elsevier Science B.V, Chapter 21;573-587, 2003. download pdf
  2. Marasco, W. A. Intrabodies as antiviral agents. Curr Top Microbiol Immunol 260, 247-270, 2001.
  3. Wheeler, YY, Chen, S-Y, Sane, DC. Intrabody and intrakine strategies for molecular therapy. Mol. Ther. 8: 355-366, 2003.

Pathfinder and StepBack Selection, Paramagnetic Proteoliposome Selection

  1. Osbourn JK, Derbyshire EJ, Vaughan TJ, Field AW, Johnson KS. Pathfinder selection: in situ isolation of novel antibodies. Immunotech. 3:293-302, 1998.
  2. Osbourn JK, Earnshaw JC, Johnson KS, Parmentier M, Timmermans V and McCafferty J. Directed selection of MIP-1a neutralizing CCR5 antibodies from a phage display human library. Nature Biotechnol. 16:778-781, 1998.
  3. Sui J, Bai J, Tallarico A, Xu C and Marasco WA. Identification of CD4 and Transferrin Receptor Antibodies by Anti-CXCR4 Antibody Guided Pathfinder Selection. Eur. J. Biochem. 2003; 270: 4497-4506. download pdf
  4. Mirzabekov T, Kontos H, Farzan M, Marasco W, Sodroski J. Paramagnetic proteoliposomes containing a pure, native, and oriented seven-transmembrane segment protein, CCR5. Nat Biotechnol. 18(6):649-54, 2000. download pdf

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