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DFCI HMS Broad

Positions

Postdoctoral position is available to lead a project focused on the biology and mechanisms of disease-relevant long non-coding RNAs (lncRNAs). The ideal candidate will have experience with RNA and protein biochemistry and molecular biology, and a desire to develop the translational potential of lncRNAs. He or she will integrate computational analyses, systems approaches, and advanced biochemical technologies to understand lncRNA biology ex vivo and in vivo. This position will work closely with other researchers and clinicians towards these goals. Interested candidates should contact Carl Novina (carl_novina@dfci.harvard.edu) for details.

Postdoctoral position is available to lead a project focused on epigenetic engineering of therapeutically-relevant genes. We recently described a novel tool for targeted DNA methylation (Scientific Reports DOI:10.1038/s41598-017-06757-0). The overarching goal of this position is to model epigenetic reprogramming fetal hemoglobin expression to model therapy of sickle cell disease and repolarization of immune cells to enhance anti-cancer immunotherapy. Interested candidates should contact Carl Novina (carl_novina@dfci.harvard.edu) for details.