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DFCI HMS Broad

Mentorship

I am deeply committed to ensuring thorough training in the scientific process for all members of my lab. Three former Postdoctoral Fellows and one Postdoctoral Fellow who trained very closely with me have become Assistant Professors. Because microRNAs and lncRNAs are regulatory molecules that are also being developed as diagnostic and therapeutic tools, universities and industries alike are interested in hiring Postdoctoral Fellows with expertise in these synergistic areas. Thus, many postdoctoral fellows have obtained Director, Investigator or Scientist II level positions in Biotech or Pharma. I am proud of the success of my past trainees and I believe I can provide a robust training environment for future scientific leaders.

The primary focus of Trainees’ work in my lab is to develop skills as an independent scientist. My lab has a strong history of technology development and implementation including microRNA and lncRNA biology and translational applications including lentiviral delivery strategies for small RNAs. Trainees work in a highly collaborative research program and use complementary genomic technologies to examine the fundamental processes underlying cancers. Trainees have access to thought leaders in single cell sequencing and analysis (including Drs. Chad Nusbaum, Chris Love), hematopoiesis (Drs. Colin Sieff, Akiko Shimamura, Alan D’Andrea), statistics and bioinformatics (Drs. Donna Neuberg, GC Yuan, Chris Burge), and clinical oncology (Drs. Stephen Hodi, Matthew Kulke, Mark Kieran, and Ursula Matulonis, to name a few). Most trainees express interest in using or developing advanced technologies to study disease processes that may also become the basis of therapy – philosophies I actively foster in my lab.

I set aside 1 hr/week to meet individually with each member of my lab. My group has a weekly lab group meeting where graduate students and postdoctoral fellows share the results of their research with other members of our group. The Department of Cancer Immunology and Virology has a weekly Floor Meeting (organized by me) where graduate students and postdoctoral fellows share the results of their research with members of our Department. Members of my group attend and occasionally present at weekly meetings of the Cancer Program at the Broad Institute, which focus on genomic approaches to cancer research, and at the Division of Immunobiology Trainee Forum. The purpose of these meetings is sharing results of projects that are in progress and on improving presentation skills. These meetings allow me to assist the development of my mentee’s skills, projects and career.