Research in the Drapkin laboratory focuses on developing a comprehensive understanding of cancer pathogenesis, DNA repair mechanisms, and genomics of women's cancers with a special focus on ovarian and breast carcinomas. The ultimate goal is to translate important principles discovered in the laboratory into clinical useful diagnostic and therapeutic tools.

To accomplish these goals, the laboratory has developed a number of enabling platforms, including robust in vitro and in vivo tools which allow us to interrogate the role of any given genetic alteration in tumor development. These model systems also allow us to evaluate changes associate with chemotherapeutic response, and to identify companion diagnostics and biomarkers for early detection.

These tools are deployed to study pathogenesis, genetics, and methods of early detection. > read more

Pathogenesis Cancer Genetics Early Detection


News from the Drapkin Lab

November 2014 -

10 big breakthroughs
coming soon

Dana-Farber Cancer Institute “We’ve created almost 50 mouse avatar models for ovarian cancer, for example,” says pathologist Ronny Drapkin, the lead investigator, ... read more.

NIH logo

July 2014 -
Congratulation to Meg on receiving the notice of award for her NIH F31 grant!!

NIH logo

May 2014 -
Ronny hosted the 33rd Annual Susan Swerling Lectures at the Dana-Farber Cancer Institute. Guest speakers included David Bowtell, Joan Brugge, and Ernst Lengyel.

Cancer Cell paper

February 2014 -
Kudos to Ruth and the rest of the team for the nice coverage of the Cancer Cell paper!

Cancer Cell paper

October 2013 -


Congratulations to the
Boston Red Sox for winning the 2013 World Championship!!

Lat at Redsox game

August 2013 -
Congratulations to Paul for getting accepted into the Oregon Health and Science University School of Medicine. We wish him all the best!

May 2013 -
Research Discussion, SSC Executive Council Breakfast | Dana-Farber Cancer Institute.
Watch Video.

April 2013 -
We are terribly saddened by the tragic events of the Boston Marathon bombings. We hope that those responsible are brought to justice and peace returns to the great city of Boston. Please consider supporting the victims of the bombing with a donation to The One Fund Boston -

The One Fund, Boston

April 2013 -
Congratulations to Kevin Elias - he is the recipient of a Firefly BioWorks Frontiers Grant Award to study SICU serum miRNAs.


January 2013 -
The Drapkin lab receives an NIH research grant to study Elafin as a biomarker for breast and ovarian cancers.


January 2013 -
The Drapkin lab receives a research grant from the Honorable Tina Brozman Foundation (Tina’s Wish) to develop novel biomarkers for the early detection of ovarian cancers.

Tina's Wish

October 2012 -
The Drapkin lab receives a research grant from the Adelson Medical Research Foundation (AMRF) to support studies on the role of mutant p53 in ovarian cancer and the development of tumor ‘avatar’ animal models from primary patient samples.


December 2012 -
Congratulations to Adam Clauss on the birth of his daughter, Sigrid Ragna Victoria Clauss, on December 5, 2012

Red Cross


October 2012 -
The Drapkin lab survived hurricane Sandy! Sadly, the storm wrecked havoc in many parts of the tri-state area. Our hearts go out to those who have been displaced from their homes or whose homes have been destroyed and those still without power and heat. Please consider making a donation to the relief efforts.
Click the logos below.

Red Cross

Red Cross


September 2012 -
Team 'Ovca Busters' raised nearly $4,000 for the 14th Annual National Ovarian Cancer Coalition (NOCC) walk-run to Break the Silence of Ovarian Cancer! Our team was made up of lab members, collaborators, and family. The event was held in South Boston at Carson Beach.

NOCC logo

April 2012 -
Congratulations to Ruth Perets for winning 1st prize at the annual retreat of the Dana-Farber Cancer Institute - Molecular and Cellular Oncology Division!


April 2012 -
Congratulations to Alison Karst – she is the recipient of the 2012 Kaleidoscope of Hope Foundation Research Award!


February 2012 -
Congratulations to Ruth on receiving the AACR - Women in Cancer Research (WICR) Scholar Award for the AACR 103rd Annual Meeting!

Sandy Rollman

August 2011 -
Ronny completed his 4th Pan Mass Challenge and raised over $6,400 for cancer research and patient care.

June 2011 -
Drapkin lab receives funding from the Sandy Rollman Ovarian Cancer Foundation to study the fallopian tube epithelium as a novel cell-of-origin for biomarker discovery in serous ovarian cancer.

Sandy Rollman

June 2011-
Team Drapkin raises over $2,800 for Ovations for the Cure of Ovarian Cancer during the 4th annual Walk-and Run (W.A.R) against ovarian cancer.


June 2011 -
Research Highlighted in National Cancer Institute Benchmarks Series

NCI logo

Spring 2010 -
Robert Wood Johnson Medicine; Young Alumni by Kate O’Neil
p 69.

October 2010 -
Congratulations to Ruth Perets on receiving the Ann Schreiber Program of Excellence grant from the Ovarian Cancer Research Fund (OCRF).

October 2010 -
Congratulations to Ronny on receiving a Travel Award to the Helene Harris Memorial Trust 12th International Forum on Ovarian Cancer.

PMC challenge

August 2010 -
Ronny completed his 3rd Pan Mass Challenge (PMC) ride and raised $4,500 for cancer research

The Mary Kay Foundation

Congratulations to Ronny for being selected as a recipient of the 2010 Research Award from the Mary Kay Foundation.

May 2010 -
Alison Karst wins the 'Poster of Distinction' at the Annual Research Celebration Day at Brigham and Women's Hospital. Four awards were selected from over 65 posters presented. Congratulations Alison!

Congratulation to Adam on the publication of his research in Neoplasia where his image was selected for the journal cover.
read paper

Keren Levanon’s recent paper in Oncogene was the 'highlighted' article.
read paper

continued on research page