The Attractin Site

Research on attractin has flourished as implementation of modern genetic techniques has identified several animal mutants with complex phenotypes resulting from mutations at the Atrn locus. Models of hair pigmentation (mahogany mice) and of tremor and neurodegeneration (zitter and myelin vacuolation rats, black tremor hamsters) all result from attractin locus mutations. Attractin plays a functional role in human immune and neural cell function, and further demonstrates primate-specific splice variants introduced by LINE retrotransposition that may play unique roles.


This site serves to collate all published information on attractin and present it in a form that will encourage further investigation. The site will be frequently updated and links to important new research directions presented in the "News" frame below.

News - updated June 19th 2016
  • The site is being updated - new links and blank pages will be filled-in in coming weeks
  • Links to abstracts and full-length papers now incorporated into Grouped Bibliography and all broken links now fixed and updated.....
  • More on prions - reduced attractin surface expression after prion infection
  • Concordant with a role in membrane trafficking, Atrn is strongly expressed during all stages of spermatogenesis
  • attractin expression is not a mediator of RML prion infection or functionality
  • Prion infection reduces post-Golgi trafficking of attractin; how does this relate to spongiform vacuolation in Atrn mutants?